Primary and Secondary Pulmonary Hypertension in Childhood: A Clinicopathological Reappraisal

摘要: In adults and older children with pulmonary hypertension the sequence of structural changes occurring in circulation relation between haemodynamic change is well recognised, following classical studies Heath Edwards (1958). However, infants young this not so, functional immature lung different from that seen adult life. Recently, improved understanding childhood has resulted (a) on normal development circulation; (b) application quantitative morphometric techniques to study vascular structure, an approach which essential a growing organ health or disease; (c) clinical care perinatal period, bringing light problem failure adapt normally extra-uterine life when heart normal; (d) angiographic haemo-dynamic evaluation, permit more accurate correlation congenital disease.