Influence of implantable cardioverter-defibrillators on the long-term prognosis of survivors of out-of-hospital cardiac arrest.
作者： A C Powell , T Fuchs , D M Finkelstein , H Garan , D S Cannom
关键词: Proportional hazards model 、 Relative risk 、 Retrospective cohort study 、 Myocardial infarction 、 Medicine 、 Ejection fraction 、 Cardiology 、 Anti-Arrhythmia Agents 、 Internal medicine 、 Sudden cardiac death 、 Sudden death
摘要: BACKGROUNDSurvivors of out-of-hospital cardiac arrest not associated with acute myocardial infarction are at high risk for recurrent and sudden death. The impact the implantable cardioverter-defibrillator on long-term prognosis in these patients is uncertain.METHODS AND RESULTSThree hundred thirty-one survivors (age, 56 +/- 13.7 years) underwent electrophysiologically guided therapy. Implantable defibrillators were placed 150 (45.3%), 181 (54.7%) received pharmacological and/or surgical therapy alone. Left ventricular ejection fraction was 35.2 16.6% defibrillator recipients 45.3 18.2% nondefibrillator patients. Median patient follow-up 24 months group 46 group. In a proportional hazards model, independent predictors total mortality left less than 0.40 (relative risk, 4.55; 95% confidence inte...
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