Desmoplastic melanoma of the eyelid and conjunctival melanoma in neurofibromatosis type 1: A clinical pathological correlation
作者： Tal J. Rubinstein , Thomas P. Plesec , Arun D. Singh
DOI: 10.1016/J.SURVOPHTHAL.2014.08.001
关键词: Hyperpigmentation 、 Biopsy 、 Neurofibromatosis 、 Dermatology 、 Pathology 、 Desmoplastic melanoma 、 Conjunctival Melanoma 、 Sentinel lymph node 、 Eyelid 、 Medicine 、 Eyelid Melanoma
摘要: A 56-year-old woman with neurofibromatosis type 1 (NF1) presented a left upper eyelid amelanotic nodule adjacent margin hyperpigmentation. Physical examination additionally revealed primary acquired melanosis (PAM) on the palpebral conjunctiva of same eyelid. Full thickness excision and conjunctival map biopsy identified desmoplastic melanoma in addition to invasive situ. Sentinel lymph node was negative for metastasis. She treated surgical topical mitomycin C melanoma. We discuss rare entity its possible association NF1.
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