作者: Natalia Jaimes , Lucy Chen , Stephen W. Dusza , Cristina Carrera , Susana Puig
DOI: 10.1001/JAMADERMATOL.2013.2248
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摘要: Objective To describe and analyze the clinical dermoscopic characteristics of desmoplastic melanoma (DM) as a function pathologic subtype phenotypic traits. Design Retrospective case series. Setting Eight high-risk dermatology clinics. Patients with DM confirmed by histopathologic analysis whose records included high-quality image. Main Outcome Measures Clinical, dermoscopic, features DM. Results A total 37 cases were identified. The majority patients had fair skin, few nevi, no history melanoma. Lentigo maligna was most frequent associated presentation palpable and/or indurated lesion located on sun-exposed skin. Forty-three percent classified pure DM, 57% mixed Pure lesions thicker than (4.10 vs 2.83 mm) (P = .22) less likely to have an epidermal non-DM component (63% 100%) (P = .004). Dermoscopically, DMs at least 1 melanoma-specific structure, being atypical vascular structures. Peppering more frequently seen in (44% 24% DM) (P = .29). In contrast, crystalline structures, polymorphous vessels, blush commonly Conclusions Though can be difficult diagnose based morphologic alone, dermoscopy has proved useful aid during evaluation clinically equivocal or those benign appearance. common clues observed peppering, occasionally other