Enhancement of intestinal growth and repair by growth factors.

作者: Gordon S Howarth , Cheryl A Shoubridge

DOI: 10.1016/S1471-4892(01)00098-4

关键词: Fibroblast Growth Factor 7BiologyKeratinocyte growth factorTGF alphaEpidermal growth factorGrowth factor receptor inhibitorCancer researchFibroblast growth factor receptor 2Transforming growth factor, beta 3EndocrinologyGrowth factorInternal medicine

摘要: Recently, glucagon-like peptide 2 has emerged as a potent stimulator of epithelial growth, joining insulin-like growth factor I, hepatocyte and keratinocyte potential treatment modalities for intestinal disorders associated with loss mucosal mass, such short bowel syndrome. Investigations into other members the expanded epidermal family, development more analogues, advances in enterally administered bioactive formulations further expands repertoire factors applicable to conditions insufficiency.

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