MR imaging in acute stroke: diffusion-weighted and perfusion imaging parameters for predicting infarct size.

作者: Hans-Jörg Wittsack , Afra Ritzl , Gereon R. Fink , Frank Wenserski , Mario Siebler

DOI: 10.1148/RADIOL.2222001731

关键词: Predictive value of testsMagnetic resonance imagingIschemiaPerfusionCentral nervous system diseaseNuclear medicineStrokeLesionPerfusion scanningMedicine

摘要: PURPOSE: To investigate the predictive value of ischemic lesion size, as depicted in acute stroke phase on diffusion-weighted magnetic resonance (MR) images and time-to-peak (TTP) maps tissue perfusion imaging, for infarct derived from T2-weighted imaging postacute phase. MATERIALS AND METHODS: Fifty patients who underwent within 1–24 hours after onset a follow-up investigation about 8 days were included. Lesion volumes evaluated by using semiautomatic thresholding technique. Volumetric results analyzed comparison with terms time difference between symptom initial MR imaging. RESULTS: At defined signal intensity increase more than 20%, compared contralateral side, showed best correlation size 1 week. per...

参考文章(17)
Alison E. Baird, Andrew Benfield, Gottfried Schlaug, Bettina Siewert, Karl-Olof Lövblad, Robert R. Edelman, Steven Warach, Enlargement of human cerebral ischemic lesion volumes measured by diffusion-weighted magnetic resonance imaging Annals of Neurology. ,vol. 41, pp. 581- 589 ,(1997) , 10.1002/ANA.410410506
D. C. Tong, M. A. Yenari, G. W. Albers, M. O'Brien, M. P. Marks, M. E. Moseley, Correlation of perfusion- and diffusion-weighted MRI with NIHSS score in acute (<6.5 hour) ischemic stroke Neurology. ,vol. 50, pp. 864- 870 ,(1998) , 10.1212/WNL.50.4.864
Tobias Neumann-Haefelin, Hans-Jörg Wittsack, Gereon R. Fink, Frank Wenserski, Tie-Qiang Li, Rüdiger J. Seitz, Mario Siebler, Ulrich Mödder, Hans-Joachim Freund, Diffusion- and Perfusion-Weighted MRI: Influence of Severe Carotid Artery Stenosis on the DWI/PWI Mismatch in Acute Stroke Stroke. ,vol. 31, pp. 1311- 1317 ,(2000) , 10.1161/01.STR.31.6.1311
Tobias Neumann-Haefelin, Hans-Jörg Wittsack, Frank Wenserski, Mario Siebler, Rüdiger J Seitz, Ulrich Mödder, Hans-Joachim Freund, None, Diffusion- and Perfusion-Weighted MRI The DWI/PWI Mismatch Region in Acute Stroke Stroke. ,vol. 30, pp. 1591- 1597 ,(1999) , 10.1161/01.STR.30.8.1591
K. Herholz, W. Buskies, M. Rist, G. Pawlik, W. Hollmann, W. D. Heiss, Regional cerebral blood flow in man at rest and during exercise. Journal of Neurology. ,vol. 234, pp. 9- 13 ,(1987) , 10.1007/BF00314001
Jeffrey L. Sunshine, Robert W. Tarr, Charles F. Lanzieri, Dennis M. D. Landis, Warren R. Selman, Jonathan S. Lewin, Hyperacute stroke: ultrafast MR imaging to triage patients prior to therapy. Radiology. ,vol. 212, pp. 325- 332 ,(1999) , 10.1148/RADIOLOGY.212.2.R99AU52325
G. Schlaug, B. Siewert, A. Benfield, R. R. Edelman, S. Warach, Time course of the apparent diffusion coefficient (ADC) abnormality in human stroke Neurology. ,vol. 49, pp. 113- 119 ,(1997) , 10.1212/WNL.49.1.113
Klaus Weinhard, Wolf-Dieter Heiss, Rudolf Graf, Jan Löttgen, Kouichi Ohta, Toshiaki Fujita, Rainer Wagner, Martin Grond, Repeat positron emission tomographic studies in transient middle cerebral artery occlusion in cats: residual perfusion and efficacy of postischemic reperfusion. Journal of Cerebral Blood Flow and Metabolism. ,vol. 17, pp. 388- 400 ,(1997) , 10.1097/00004647-199704000-00004
Steven Warach, John F. Dashe, Robert R. Edelman, Clinical outcome in ischemic stroke predicted by early diffusion-weighted and perfusion magnetic resonance imaging: a preliminary analysis Journal of Cerebral Blood Flow and Metabolism. ,vol. 16, pp. 53- 59 ,(1996) , 10.1097/00004647-199601000-00006