Hepatitis B and C Virus Infections in Hepatocellular Carcinoma and Their Prevention

摘要: Although the etiology of chronic liver disease and hepatocellular carcinoma (HCC) varies in different parts world, hepatitis viruses are most important etiologic factor. Recently, use sensitive specific assays, including polymerase chain reaction (PCR), has greatly contributed to understanding HCC. For example, Taiwan, HCC is commonly associated with persistent B virus (HBV) infection, surface antigen (HBsAg) found 80%–90% patients investigated. Hepatitis C (HCV) next common, an anti-HCV prevalence about 70% HBsAg-negative patients. Overall, 10%–15% have dual infections HBV HCV. In HBsAg-negative/anti-HCV-negative patients, HCV-RNA or HBV- DNA can be shown by PCR at least half cases, thus still suggesting role both viruses.