Solid and cystic acinar cell tumour of the pancreas. A tumour in young women with favourable prognosis.

作者: G. Kl�ppel , T. Morohoshi , H. D. John , W. Oehmichen , K. Opitz

DOI: 10.1007/BF00430819

关键词: PathologyPancreasSolid pseudopapillary tumourPoor prognosisBiologyAcinar cell tumourIntracellularLesionUltrastructureWho classification

摘要: The clinico-pathological features of five cases with a distinctive pancreatic tumour are presented. tumours, which occurred only in young women and an adolescent girl, were large size (2.5–10 cm), had uncharacteristic symptomatology showed fibrous encapsulation no evidence metastases. histological include (1) solid areas monomorphic cell pattern intracellular PAS positive globules, (2) foci degeneration cystic necroses, haemorrhages cholesterol granulomas. Some cells for α1-antitrypsin. ultrastructural demonstration zymogen-like granules suggests acinar origin the tumours. We therefore propose term tumour. This resembles so called pancreatoblastomas small children some respects. It must be clearly distinguished, on other hand, from carcinoma its acinic structures poor prognosis. lesion is not included WHO classification neoplasms.

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