The Human Connectome

摘要: Publisher Summary The human brain is a complex and highly dynamic biological network, the physical structure of which still only partially mapped. This chapter provides an overview how analysis comprehensive maps structural connectivity, connectome, may benefit our understanding structure–function relationships in brain. Such description will serve as fundamental research tool for works system. A major distinction among descriptions networks that structural, functional, effective connectivity. pattern connections likely to influence patterns functional interactions between regions, such turn are have effects on their own physiological efficacy or strength, through mechanisms activity- experience-dependent plasticity. Structural connectivity describes network connections, correspond fiber pathways individual synapses. basic elements not easily defined, because brain's intrinsic multiscale architecture many linkages across these different levels determine function. incentive deriving connectome power mathematical tools available study networks. One useful attributes applicability both functional/effective data sets. Future advances diffusion imaging other non-invasive mapping technologies allow construction detailed map subjects. sets prove valuable detecting connectional correlates neurological psychiatric conditions brain, predicting cognitive behavioral performance.