Management of intracranial hemorrhage in adult patients on extracorporeal membrane oxygenation (ECMO): An observational cohort study.

摘要: Background Intracranial hemorrhage (ICH) is a common complication in adults treated with extracorporeal membrane oxygenation (ECMO). The aim of this study was to identify predictors outcome and investigate intervention strategies following ICH development ECMO-treated adult patients. Methods We conducted retrospective review patients (≥18 years) who developed an during ECMO treatment at the Karolinska University Hospital (Stockholm, Sweden) between September 2005 May 2017. Outcome assessed by 30-day mortality Glasgow Scale (GOS) after 6 months. statistical analysis supplemented case series were surgically for ICH. Results Sixty-five treatment. 74% (n = 48), significantly associated low level consciousness diagnosis (p 0.036), presence intraparenchymal hematoma (IPH) 0.049), IPH volume 0.002), intraventricular 0.001), subarachnoid Fisher grade (p<0.001), hydrocephalus midline shift 0.026) absent basal cisterns (p<0.001). Among survivors 17), 63% 10) had favorable neurological (GOS 4–5) six Five their ICH, some dire hemorrhagic consequences, however one patient made complete recovery. Conclusions high rate. can help where indicated. Treating represents intricate balance pro- anticoagulatory demands. Furthermore, surgical several risks but may be indicated life-threatening lesions. Prospective studies are warranted.