Demonstration of a phosphazirconocene as a catalyst for the ring opening of epoxides with TMSCl.
作者： Li-Sheng Wang , T. Keith Hollis
DOI: 10.1021/OL034816R
关键词: Reactivity (chemistry) 、 Ring (chemistry) 、 Organic chemistry 、 Stereoselectivity 、 Chlorohydrins 、 Chemistry 、 Transition metal 、 Catalysis
摘要: In this study, it was demonstrated for the first time that a phosphazirconocene catalyzes ring opening of epoxides with TMSCl. This reactivity leads to facile preparation chlorohydrins. The late transition metal Fe analogue found catalyze reaction at rates and stereoselectivity comparable those Zr complex.
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