Clinical Outcomes Among Children With Standard-Risk Medulloblastoma Treated With Proton and Photon Radiation Therapy: A Comparison of Disease Control and Overall Survival
作者： Bree R. Eaton , Natia Esiashvili , Sungjin Kim , Elizabeth A. Weyman , Lauren T. Thornton
DOI: 10.1016/J.IJROBP.2015.09.014
关键词: Proton therapy 、 Chemotherapy 、 Histology 、 Photon radiation therapy 、 Medulloblastoma 、 Nuclear medicine 、 Young adult 、 Cohort study 、 Medicine 、 Confidence interval
摘要: Purpose The purpose of this study was to compare long-term disease control and overall survival between children treated with proton and photon radiation therapy (RT) for standard-risk medulloblastoma. Methods and Materials This multi-institution cohort study includes 88 children treated with chemotherapy and proton (n= 45) or photon (n= 43) RT between 2000 and 2009. Overall survival (OS), recurrence-free survival (RFS), and patterns of failure were compared between the 2 cohorts. Results Median (range) age was 6 years old at diagnosis …
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