Proton therapy for pediatric cancer: are we ready for prime time?

Roshan V. Sethi, Helen A. Shih, Beow Y. Yeap, Kent W. Mouw, Robert Petersen, David Y. Kim, John E. Munzenrider, Eric Grabowski, Carlos Rodriguez-Galindo, Torunn I. Yock, Nancy J. Tarbell, Karen J. Marcus, Shizuo Mukai, Shannon M. MacDonald, Second nonocular tumors among survivors of retinoblastoma treated with contemporary photon and proton radiotherapy Cancer. ,vol. 120, pp. 126- 133 ,(2014) , 10.1002/CNCR.28387

Raymond B. Mailhot Vega, Jane Kim, Marc Bussière, Jona Hattangadi, Abby Hollander, Jeff Michalski, Nancy J. Tarbell, Torunn Yock, Shannon M. MacDonald, Cost effectiveness of proton therapy compared with photon therapy in the management of pediatric medulloblastoma. Cancer. ,vol. 119, pp. 4299- 4307 ,(2013) , 10.1002/CNCR.28322

Raymond Mailhot Vega, Jane Kim, Abby Hollander, Jona Hattangadi-Gluth, Jeff Michalski, Nancy J. Tarbell, Torunn I. Yock, Marc Bussiere, Shannon M. MacDonald, Cost effectiveness of proton versus photon radiation therapy with respect to the risk of growth hormone deficiency in children. Cancer. ,vol. 121, pp. 1694- 1702 ,(2015) , 10.1002/CNCR.29209

Drosoula Giantsoudi, Roshan V. Sethi, Beow Y. Yeap, Bree R. Eaton, David H. Ebb, Paul A. Caruso, Otto Rapalino, Yen-Lin E. Chen, Judith A. Adams, Torunn I. Yock, Nancy J. Tarbell, Harald Paganetti, Shannon M. MacDonald, Incidence of CNS Injury for a Cohort of 111 Patients Treated With Proton Therapy for Medulloblastoma: LET and RBE Associations for Areas of Injury International Journal of Radiation Oncology Biology Physics. ,vol. 95, pp. 287- 296 ,(2016) , 10.1016/J.IJROBP.2015.09.015

Bree R. Eaton, Natia Esiashvili, Sungjin Kim, Elizabeth A. Weyman, Lauren T. Thornton, Claire Mazewski, Tobey MacDonald, David Ebb, Shannon M. MacDonald, Nancy J. Tarbell, Torunn I. Yock, Clinical Outcomes Among Children With Standard-Risk Medulloblastoma Treated With Proton and Photon Radiation Therapy: A Comparison of Disease Control and Overall Survival International Journal of Radiation Oncology Biology Physics. ,vol. 94, pp. 133- 138 ,(2016) , 10.1016/J.IJROBP.2015.09.014

Nataniel H. Lester-Coll, Christopher B. Morse, Huifang A. Zhai, Stefan Both, Jill P. Ginsberg, Clarisa R. Gracia, Robert A. Lustig, Zelig Tochner, Christine E. Hill-Kayser, Preserving Fertility in Adolescent Girls and Young Women Requiring Craniospinal Irradiation: A Case Report and Discussion of Options to Be Considered Prior to Treatment. Journal of adolescent and young adult oncology. ,vol. 3, pp. 96- 99 ,(2014) , 10.1089/JAYAO.2013.0038

Bradford S. Hoppe, Stella Flampouri, Zhong Su, Naeem Latif, Nam H. Dang, James Lynch, Michael Joyce, Eric Sandler, Zuofeng Li, Nancy P. Mendenhall, Effective Dose Reduction to Cardiac Structures Using Protons Compared With 3DCRT and IMRT in Mediastinal Hodgkin Lymphoma International Journal of Radiation Oncology*Biology*Physics. ,vol. 84, pp. 449- 455 ,(2012) , 10.1016/J.IJROBP.2011.12.034

Peter A.S. Johnstone, John Kerstiens, Doing poorly by doing good: the bottom line of proton therapy for children. Journal of The American College of Radiology. ,vol. 11, pp. 995- 997 ,(2014) , 10.1016/J.JACR.2014.04.004

Thomas E. Merchant, Chia-ho Hua, Hemant Shukla, Xiaofei Ying, Simeon Nill, Uwe Oelfke, Proton versus photon radiotherapy for common pediatric brain tumors: Comparison of models of dose characteristics and their relationship to cognitive function Pediatric Blood & Cancer. ,vol. 51, pp. 110- 117 ,(2008) , 10.1002/PBC.21530

Rui Zhang, Rebecca M. Howell, Phillip J. Taddei, Annelise Giebeler, Anita Mahajan, Wayne D. Newhauser, A comparative study on the risks of radiogenic second cancers and cardiac mortality in a set of pediatric medulloblastoma patients treated with photon or proton craniospinal irradiation. Radiotherapy and Oncology. ,vol. 113, pp. 84- 88 ,(2014) , 10.1016/J.RADONC.2014.07.003