The clinical significance of fever in acute leukemia.

作者: SPENCER O. RAAB , PAUL D. HOEPRICH , MAXWELL M. WINTROBE , GEORGE E. CARTWRIGHT

DOI: 10.1182/BLOOD.V16.5.1609.1609

关键词: Absolute numberClinical significanceLeukemiaInternal medicinePathogenesisMedicineImmunologyPhysical examinationLymphoblastic LeukemiaAcute leukemiaBlood culture

摘要: 1. The total course of acute leukemia in 55 patients managed one clinic disclosed 149 febrile episodes. 2. Fever occurred virtually only when the was relapse. 3. Infection cause fever 102 episodes fever. 4. With survival after onset symptoms beyond mean duration life characteristic that kind leukemia, infection appeared to be more often than less for leukemia. 5. due could not reliably differentiated from by either height or character curve, counting absolute number mature polymorphonuclear leukocytes blood. 6. causing most successfully detected means history, physical examination, chest roentgenogram, blood culture and other cultures as indicated preceding maneuvers. 7. Consideration point view present day studies pathogenesis did clearly implicate known mechanisms pyrogenesis. 8. interplay state nature infecting microorganism anti-infectious antileukemic therapies is related outcome infections. management discussed. 9. Increased time children with lymphoblastic has been accompanied increased morbidity.

参考文章(7)
RICHARD T. SILVER, GRACE A. BEAL, MARVIN A. SCHNEIDERMAN, NORMAN B. MCCULLOUGH, The role of the mature neutrophil in bacterial infections in acute leukemia. Blood. ,vol. 12, pp. 814- 821 ,(1957) , 10.1182/BLOOD.V12.9.814.814
Richard T. Silver, John P. Utz, Emil Frei, Norman B. McCullough, Fever, infection and host resistance in acute leukemia The American Journal of Medicine. ,vol. 24, pp. 25- 39 ,(1958) , 10.1016/0002-9343(58)90359-0
ROBERT G. PETERSDORF, The Experimental Approach to the Mechanism of Fever Archives of Internal Medicine. ,vol. 103, pp. 991- 1001 ,(1959) , 10.1001/ARCHINTE.1959.00270060143021
Harold Tivey, The natural history of untreated acute leukemia. Annals of the New York Academy of Sciences. ,vol. 60, pp. 322- 358 ,(1954) , 10.1111/J.1749-6632.1954.TB40023.X
Maurice Landy, Murray J. Shear, , SIMILARITY OF HOST RESPONSES ELICITED BY POLYSACCHARIDES OF ANIMAL AND PLANT ORIGIN AND BY BACTERIAL ENDOTOXINS Journal of Experimental Medicine. ,vol. 106, pp. 77- 97 ,(1957) , 10.1084/JEM.106.1.77