Terpenoids: natural products for cancer therapy.
作者： Min Huang , Jin-Jian Lu , Ming-Qing Huang , Jiao-Lin Bao , Xiu-Ping Chen
DOI: 10.1517/13543784.2012.727395
关键词: Cancer therapy 、 Terpenoid 、 Triterpenoid 、 Biology 、 Identification (biology) 、 Cancer cell proliferation 、 Traditional medicine 、 Drug discovery
摘要: Introduction: Terpenoids constitute the largest class of natural products and are a rich reservoir candidate compounds for drug discovery. Recent efforts into research development anti-cancer drugs derived from have led to identification variety terpenoids that inhibit cancer cell proliferation metastasis via various mechanisms. Despite increasing number reports, there lacks comprehensive review activity terpenoids. Areas covered: The present article provides an overview recent progress in studies on Over dozen naturally originated terpenoid compounds, particular those traditional Chinese medicine, were classified five categories according structures, namely monoterpenoids, sesquiterpenoids, diterpenoids, triterpenoids tetraterpenoids. activities relevant mechanistic insights these discussed this review. Expert opini...
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