Downregulation of HDAC9 inhibits cell proliferation and tumor formation by inducing cell cycle arrest in retinoblastoma.
作者： Fengjie Xia , Hongyu Xian , Xinyue Zhu , Hongjuan Cui , Zhenping Huang
DOI: 10.1016/J.BBRC.2016.03.129
关键词: Retinoblastoma 、 Cell cycle 、 Cancer research 、 Cell growth 、 Cell cycle checkpoint 、 Biology 、 HDAC9 、 Cyclin-dependent kinase 2 、 Downregulation and upregulation 、 Cyclin E2
摘要: … Lastly, xenograft study in nude mice showed that downregulation of HDAC9 inhibited tumor growth and development in vivo. Therefore, our results suggest that HDAC9 could serve as a …
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