作者: C.A Ahene , R.W Lea , S Harvey
DOI: 10.1016/0300-9629(91)90585-Z
关键词: Growth hormone secretion 、 Biology 、 Thyrotropin-releasing hormone 、 Neuropeptide 、 Somatostatin 、 Internal medicine 、 Basal (phylogenetics) 、 Secretion 、 Central nervous system 、 Endocrinology 、 Hormone
摘要: 1. Basal circulating growth hormone (GH) concentrations in sex-linked-dwarf (SLD) chickens were unaffected by the intracerebroventricular (icv) injection of 10, 50 or 100 micrograms somatostatin (SRIF). 2. The GH response to systemic thyrotropin-releasing (TRH; 10 micrograms/kg, iv) was, however, 'paradoxically' enhanced 20 min after icv SRIF administration. 3. A lower dose (1.0 micrograms) had no effect on basal TRH-induced release. 4. High-titre antisera (4 microliters) also acute plasma concentrations, but augmented TRH challenge. 5. would appear act at central sites modulate stimulated secretion SLD chickens.