作者: Hendrian Dwikoloso Soebagjo , Hidayat Sujuti , Hasan Machfoed , Sutiman Bambang Soemitro , None
DOI:
关键词: Chemistry 、 Immunohistochemistry 、 Cancer research 、 Protein expression 、 Fas ligand 、 Paraffin Block 、 Retinoblastoma
摘要: Purpose: The aim of this study were to determine the association increasing FasL with proliferation retinoblastoma cells. Materials and Methods: protein expression was analyzed in 30 samples from paraffin block using immunohistochemical method for evaluation FasL, CDK4, Ki-67 expression. Results: Among samples, majority negative 33.3 % (10 samples) strong 36,8 (11 samples). CDK4 53,3% weak high also (16 significantly related (r: 0.363; p: 0.048). 0.601; 0.000). Conclusion: on mechanism Fas counterattack induces cells.