Adult living donor versus deceased donor liver transplantation: a 6-year single center experience.

作者: Daniel G. Maluf , Richard Todd Stravitz , Adrian H. Cotterell , Marc P. Posner , Mitsuru Nakatsuka

DOI: 10.1111/J.1600-6143.2004.00654.X

关键词: SurgeryHepatitis C virusProportional hazards modelProspective cohort studyPerioperativeLiver transplantationMedicineTransplantationSingle CenterLiver disease

摘要: No long-term (>3 years) prospective comparison of adult-to-adult living donor liver transplantation (A2ALLTx) to adult deceased (ADDLTx) has been reported. This is a prospective, IRB approved, 6-year A2ALLTx ADDLTx. Data include: age, gender, ethnicity, primary disease, waiting time, pretransplant CTP/MELD score, cold ischemia time (CIT), perioperative mortality, acute and chronic rejection, graft patient survival, charges post-transplant complications. In 6 years, 202 ADDLTx (74.5%) 69 (25.5%) were performed at VCUHS. Hepatitis C virus (HCV) was the most common reason for in both groups (48.1% vs. 42%). regarding overall monetary retransplantation rates similar. Comparison patient/graft survivals, patients with without HCV not statistically different. had less rejection (11.5% 23.9%) more biliary complications (26.1% 11.4%). Overall, as durable replacement technique Patients younger, lower MELD scores, similar histological recurrence. Biliary but associated increased loss compared

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