Structures and Mechanisms of Nudix Hydrolases
作者： A.S. Mildvan , Z. Xia , H.F. Azurmendi , V. Saraswat , P.M. Legler
DOI: 10.1016/J.ABB.2004.08.017
关键词: Nucleophile 、 Nucleophilic substitution 、 Divalent 、 Leaving group 、 Stereochemistry 、 Nudix hydrolase 、 Hydrolase 、 Histidine 、 Chemistry 、 Organic chemistry 、 Lewis acid catalysis
摘要: … To explain the catalytic versatility of the Nudix superfamily of enzymes, this review will initially focus on the four Nudix enzymes with the most diverse mechanisms: the MutT …
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