Phase separation in aqueous solutions of polyethylaminophosphazene hydrochloride during heating
作者： V. Ya. Grinberg , N. V. Grinberg , T. V. Burova , A. S. Dubovik , D. R. Tur
DOI: 10.1134/S0965545X10110167
关键词: Hydrochloride 、 Polymer 、 Analytical chemistry 、 Lower critical solution temperature 、 Dehydration 、 Phase diagram 、 Aqueous solution 、 Enthalpy 、 Chromatography 、 Molecule 、 Chemistry
摘要: It is shown that aqueous solutions of polyethylaminophosphazene hydrochloride undergo phase separation during heating. This phenomenon studied in detail at pH 3.5 (0.1 M citrate buffer) relation to the composition system with use nephelometry and high-sensitivity DSC. The cloud points enthalpy are determined, its diagram constructed. features a lower critical solution temperature: w2,cr = 7.3 × 10−4 Tcr 34.3°C. 12.8 ± 0.6 J/g polymer, regardless composition. A new approach analysis DSC data on polymers heating advanced basis calorimetric parameters coupled coexisting phases. Through this approach, main contribution heat effect under study related change energy state molecule as result dehydration.
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sci-hub.se 参考文章(40)
Peter L. Privalov, Sergey A. Potekhin, [2]Scanning microcalorimetry in studying temperature-induced changes in proteins Methods in Enzymology. ,vol. 131, pp. 4- 51 ,(1986) , 10.1016/0076-6879(86)31033-4
Thermodynamic data for biochemistry and biotechnology Springer Berlin Heidelberg. ,(1986) , 10.1007/978-3-642-71114-5
Byeongmoon Jeong, You Han Bae, Doo Sung Lee, Sung Wan Kim, Biodegradable block copolymers as injectable drug-delivery systems Nature. ,vol. 388, pp. 860- 862 ,(1997) , 10.1038/42218
Charles Tanford, Physical Chemistry of Macromolecules ,(1961)
Ruixue Liu, Michael Fraylich, Brian R. Saunders, Thermoresponsive copolymers: from fundamental studies to applications Colloid and Polymer Science. ,vol. 287, pp. 627- 643 ,(2009) , 10.1007/S00396-009-2028-X
A. S. Dubovik, N. V. Grinberg, V. Ya. Grinberg, Energetics of phase separation in aqueous solutions of poly( N -isopropylacrylamide) Polymer Science Series A. ,vol. 52, pp. 565- 573 ,(2010) , 10.1134/S0965545X10060015
R. Koningsveld, A. J. Staverman, Liquid–liquid phase separation in multicomponent polymer solutions. II. The critical state Journal of Polymer Science Part A-2: Polymer Physics. ,vol. 6, pp. 325- 347 ,(1968) , 10.1002/POL.1968.160060202
Alexander S. Dubovik, Elena E. Makhaeva, Valerij Ya. Grinberg, Alexei R. Khokhlov, Energetics of Cooperative Transitions of N-Vinylcaprolactam Polymers in Aqueous Solutions Macromolecular Chemistry and Physics. ,vol. 206, pp. 915- 928 ,(2005) , 10.1002/MACP.200400554
Sungsook Ahn, Estela C. Monge, Soo-Chang Song, Ion and pH Effect on the Lower Critical Solution Temperature Phase Behavior in Neutral and Acidic Poly(organophosphazene) Counterparts Langmuir. ,vol. 25, pp. 2407- 2418 ,(2009) , 10.1021/LA802815U
Sun Mi Lee, Chang Ju Chun, Jeong Yun Heo, Soo-Chang Song, Injectable and thermosensitive poly(organophosphazene) hydrogels for a 5-fluorouracil delivery Journal of Applied Polymer Science. ,vol. 113, pp. 3831- 3839 ,(2009) , 10.1002/APP.30397