Thermodynamic insight into the thermoresponsive behavior of chitosan in aqueous solutions: A differential scanning calorimetry study.

摘要: Abstract Thermoresponsivity of chitosan induced by β-glycerophosphate (GP) in diluted aqueous solutions has been first studied high-sensitivity differential scanning calorimetry. It found that the GP undergo a first-order phase transition upon heating. The onset this coincides with cloud point system. This allows one to identify thermoresponsivity as macroscopic demonstration separation transition. temperature, enthalpy, heat capacity increment, and width were determined functions concentrations, dielectric constant solvent. Based on data, we suggested binds cooperatively matrix at low temperatures. standard free energy binding ( Δ b g int = −6 ± 1 kJ mol−1) was estimated from DSC data. shown Okada–Tanaka model cooperative hydration polymers adequately describes thermogram chitosan.