Adipose tissue lipolysis and energy metabolism in early cancer cachexia in mice.

作者: Kara L Kliewer , Jia-Yu Ke , Min Tian , Rachel M Cole , Rebecca R Andridge

DOI: 10.4161/15384047.2014.987075

关键词: Lipid metabolismWeight lossEndocrinologyBiologyWhite adipose tissueInternal medicineMetabolic disorderThermogenesisLipolysisCachexiaAdipose tissue

摘要: … -26 murine model of cachexia. White adipose tissue mass in … weight in this study of early cachexia. In white adipose depots … energy expenditure and increased expression of markers of …

参考文章(68)
Carolyn Cray, Julia Zaias, Norman H Altman, Acute phase response in animals: a review. Comparative Medicine. ,vol. 59, pp. 517- 526 ,(2009)
Kazuo Yasumoto, Naofumi Mukaida, Akihisa Harada, Kouji Kuno, Mariko Akiyama, Emiko Nakashima, Nakaba Fujioka, Masayoshi Mai, Tadashi Kasahara, Karoi Fujimoto-Ouchi, Kazushige Mori, Yutaka Tanaka, Kouji Matsushima, None, Molecular Analysis of the Cytokine Network Involved in Cachexia in Colon 26 Adenocarcinoma-bearing Mice Cancer Research. ,vol. 55, pp. 921- 927 ,(1995)
Chen Bing, Michael J. Tisdale, Peter King, Michael Brown, Peter Collins, Gareth Williams, Increased Gene Expression of Brown Fat Uncoupling Protein (UCP)1 and Skeletal Muscle UCP2 and UCP3 in MAC16-induced Cancer Cachexia Cancer Research. ,vol. 60, pp. 2405- 2410 ,(2000)
Ikuo Horii, Hideo Ishitsuka, Tetsuo Taguchi, Tohru Ishikawa, Hiroyuki Eda, Tateshi Kataoka, Takashi Tanaka, Toshiaki Udagawa, Yutaka Tanaka, Experimental Cancer Cachexia Induced by Transplantable Colon 26 Adenocarcinoma in Mice Cancer Research. ,vol. 50, pp. 2290- 2295 ,(1990)
J. A. McLean, G. Tobin, Animal and Human Calorimetry ,(1988)
Murray R. Grigor, Jean E. Koons, Mary P. Thompson, Edward T. H. Tan, Modified Lipoprotein Lipase Activities, Rates of Lipogenesis, and Lipolysis as Factors Leading to Lipid Depletion in C57BL Mice Bearing the Preputial Gland Tumor, ESR-586 Cancer Research. ,vol. 41, pp. 3228- 3232 ,(1981)
Serkan Kir, James P. White, Sandra Kleiner, Lawrence Kazak, Paul Cohen, Vickie E. Baracos, Bruce M. Spiegelman, Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia Nature. ,vol. 513, pp. 100- 104 ,(2014) , 10.1038/NATURE13528
SJ Wigmore, JS Falconer, CE Plester, JA Ross, JP Maingay, DC Carter, KCH Fearon, Ibuprofen reduces energy expenditure and acute-phase protein production compared with placebo in pancreatic cancer patients British Journal of Cancer. ,vol. 72, pp. 185- 188 ,(1995) , 10.1038/BJC.1995.300
I Dahlman, N Mejhert, K Linder, T Agustsson, D M Mutch, A Kulyte, B Isaksson, J Permert, N Petrovic, J Nedergaard, E Sjölin, D Brodin, K Clement, K Dahlman-Wright, M Rydén, P Arner, Adipose tissue pathways involved in weight loss of cancer cachexia British Journal of Cancer. ,vol. 102, pp. 1541- 1548 ,(2010) , 10.1038/SJ.BJC.6605665
Benjamin HL Tan, Kenneth CH Fearon, Cachexia: prevalence and impact in medicine. Current Opinion in Clinical Nutrition and Metabolic Care. ,vol. 11, pp. 400- 407 ,(2008) , 10.1097/MCO.0B013E328300ECC1