Activation of the cell stress kinase PKR in Alzheimer’s disease and human amyloid precursor protein transgenic mice
作者： Alyson L Peel , Dale E Bredesen
DOI: 10.1016/S0969-9961(03)00086-X
关键词: Senile plaques 、 Amyloid precursor protein 、 Protein kinase R 、 Amyloid beta 、 Alzheimer's disease 、 BACE1-AS 、 Protein kinase A 、 EIF-2 kinase 、 Neuroscience 、 Cell biology 、 Biology
摘要: … cell death, we observed that a stress-activated kinase, PKR, … The presence of activated PKR in association with AD … with stress-mediated mechanisms of cell death and it is considered …
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