Risk factors for hepatitis C virus infection among blood donors in Israel: a case-control study between native Israelis and immigrants from the former Soviet Union.

摘要: BACKGROUND: The annual hepatitis C virus (HCV) seropositivity prevalence among blood donors (BDs) in Israel is 0.1 percent. Although only 10 percent of the BD population are immigrants from former Soviet Union (FSUIs), they represent 80 percent HCV-seropositive cases. This study aimed to identify HCV risk factors Native Israeli (NI) and FSUI BDs, determine if specific interventions needed. STUDY DESIGN AND METHODS: Two case-control studies were designed, interviewing 178 HCV-positive cases (128 FSUIs, 50 NIs) 256 HCV-negative controls 128 NIs). All participants volunteer BDs Magen David Adom (MDA) Blood Services. RESULTS: A total 434 985 mailed letters consented be interviewed (44% response rate), without differences compliance between populations. In both, intravenous drug use (IVDU) was strongest seropositivity–associated factor. After IVDU adjustment, important age, transfusion before 1990, first-time donation, not practicing teeth cleaning. Close contact with people at for (odds ratio [OR], 7.2; 95% confidence interval [CI], 1.9-27.8) surgery (OR, 7.3; CI, 1.6-34.4) strong NIs, whereas gum 7.6; 1.1-52.3), hospitalization 2.6; 1.1-6.5), therapy injection form 4.9; 2.4-10.2) merely found probably resulting inadequate aseptic conditions. ORs surgery, index, first donation differed significantly two populations. CONCLUSION: strength differs immigrant most studied did differ groups. Therefore, changes screening all considered.