Epidemiological and clinical aspects of hepatitis C virus infection in the Russian Republic of Daghestan

摘要: Hepatitis C virus (HCV) is a leading cause of chronic liver disease. The prevalence in blood donors the USA and West Europe around 0.3%. However, there are few studies performed East Europe. We have studied hepatitis infection risk factors associated with it Russian Republic Daghestan. Population methods: included 10,682 volunteer donors, 267 commercial 97 high patients (22 haemophiliacs, 41 haemodialysis program 34 parenteral drug addicts), 87 disease (61 hepatitis, 20 cirrhosis 6 hepatocellular carcinoma). Antibodies against HCV were detected by second generation ELISA. Results: 0.93% found to be reactive. Factors stronger association seropositivity previous transfusion addiction. 66% seropositive had an elevated level ALT. Alcohol use correlated more marked deterioration function tests. 7.5% seropositive. Prevalence was very (50–80% 40–50%, respectively). Conclusion: Daghestan has one lowest rates Commercial infection. similar those other epidemiological studies.