Effects of baclofen and γ-aminobutyric acid on different types of medullary respiratory neurons
作者： Peter M. Lalley
DOI: 10.1016/0006-8993(86)90206-4
关键词: Baclofen 、 Anesthesia 、 Phrenic nerve 、 Central nervous system 、 Aminobutyric acid 、 Endocrinology 、 Medullary cavity 、 Disinhibition 、 Respiratory system 、 Neuron 、 Internal medicine 、 Medicine 、 Developmental biology 、 General Neuroscience 、 Molecular biology 、 Clinical neurology
摘要: Abstract Effects of baclofen and γ-aminobutyric acid on medullary respiratory neurons were investigated. Medullary inspiratory the dorsal ventral groups stimulated by baclofen, 0.5–2 mg/kg, depressed doses greater than 4–6 mg/kg. Expiratory which increased phrenic nerve activity. Microelectrophoresis (5 mM, pH 3) neurons. It is suggested that low i.v. increase activity disinhibition whereas higher directly depress
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