Methadone enantiomer plasma levels, CYP2B6, CYP2C19, and CYP2C9 genotypes, and response to treatment
作者： S CRETTOL , J DEGLON , J BESSON , M CROQUETTEKROKKAR , I GOTHUEY
DOI: 10.1016/J.CLPT.2005.08.011
关键词: Endocrinology 、 Pharmacology 、 Chemistry 、 Pharmacokinetics 、 Methadone maintenance 、 Methadone 、 Dose 、 Internal medicine 、 Opioid 、 CYP2C9 、 Blood plasma 、 CYP2C19
摘要: Background and Objective Recent in vitro studies have suggested an important role of cytochrome P450 (CYP) 2B6 and CYP2C19 in methadone metabolism. We aimed to …
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