The CT flare response of metastatic bone disease in prostate cancer.
作者： Christina Messiou , Gary Cook , Alison HM Reid , Gerhardt Attard , David Dearnaley
关键词: Prostate 、 Bone scintigraphy 、 Metastasis 、 Cancer 、 Prostate-specific antigen 、 Bone disease 、 Medicine 、 Cancer biomarkers 、 Pathology 、 Prostate cancer
摘要: BackgroundNew or worsening bone lesions in patients responding to treatment, known as the flare phenomenon is well described on 99mTc-MDP scintigraphy, but our knowledge has not previously been CT. The appearance of new sclerosis CT with prostate cancer may therefore be erroneously classified disease progression.PurposeTo assess incidence osteoblastic healing response at 3-month assessment castrate-resistant and identify associated features that enable differentiation from progressive metastatic 3 months.Material MethodsCT scans 67 undergoing treatment were reviewed by a radiologist blinded clinical outcome. Changes number, size, density documented Response Evaluation Criteria Solid Tumours (RECIST) soft tissue lesions, alkaline phosphatase, specific antigen, 99mT...
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