Role of reactive oxygen species in the neurotoxicity of environmental agents implicated in Parkinson's disease.
作者： Derek A. Drechsel , Manisha Patel
DOI: 10.1016/J.FREERADBIOMED.2008.02.008
关键词: Disease 、 Neuroscience 、 Oxidative stress 、 Biology 、 Biochemistry 、 Toxicant 、 Neurodegeneration 、 Parkinson's disease 、 Dopaminergic Cell 、 Reactive nitrogen species 、 Neurotoxicity
摘要: … Decreased complex I activity in the mitochondrial respiratory … the same transport system as DA and norepinephrine to produce … PQ is a quick-acting, nonselective herbicide that destroys …
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Anthony E. Lang, Andres M. Lozano, Parkinson's disease. First of two parts. The New England Journal of Medicine. ,vol. 339, pp. 1044- 1053 ,(1998) , 10.1056/NEJM199810083391506
T Fukushima, K Yamada, A Isobe, K Shiwaku, Y Yamane, None, Mechanism of cytotoxicity of paraquat Experimental and Toxicologic Pathology. ,vol. 45, pp. 345- 349 ,(1993) , 10.1016/S0940-2993(11)80424-0
Fiona Thomson, Parkinson's Disease Neuron. ,vol. 39, pp. 889- 909 ,(2003) , 10.1016/S0896-6273(03)00568-3
L. L. Smith, Young Scientists Award Lecture 1981: The Identification of an Accumulation System for Diamines and Polyamines Into the Lung and Its Relevance to Paraquat Toxicity Archives of Toxicology. ,vol. 5, pp. 1- 14 ,(1982) , 10.1007/978-3-642-68511-8_1
David O. Carpenter, Effects of metals on the nervous system of humans and animals. International Journal of Occupational Medicine and Environmental Health. ,vol. 14, pp. 209- 218 ,(2001)
C M Tanner, J W Langston, Do environmental toxins cause Parkinson's disease? A critical review. Neurology. ,vol. 40, pp. 17- 31 ,(1990)
Julie K. Andersen, Iron dysregulation and Parkinson's disease. Journal of Alzheimer's Disease. ,vol. 6, ,(2005) , 10.3233/JAD-2004-6S602
Ranjita Betarbet, Todd B. Sherer, Gillian MacKenzie, Monica Garcia-Osuna, Alexander V. Panov, J. Timothy Greenamyre, Chronic systemic pesticide exposure reproduces features of Parkinson's disease Nature Neuroscience. ,vol. 3, pp. 1301- 1306 ,(2000) , 10.1038/81834
Gabriel T. Liberatore, Vernice Jackson-Lewis, Slobodanka Vukosavic, Allen S. Mandir, Miquel Vila, W. Geoffrey McAuliffe, Valina L. Dawson, Ted M. Dawson, Serge Przedborski, Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease Nature Medicine. ,vol. 5, pp. 1403- 1409 ,(1999) , 10.1038/70978
Y Zhang, O Marcillat, C Giulivi, L Ernster, K J Davies, The oxidative inactivation of mitochondrial electron transport chain components and ATPase. Journal of Biological Chemistry. ,vol. 265, pp. 16330- 16336 ,(1990) , 10.1016/S0021-9258(17)46227-2