Sympathetic neural contribution to salt-induced hypertension in Dahl rats.
作者： A. L. Mark
DOI: 10.1161/01.HYP.17.1_SUPPL.I86
关键词: Afferent 、 Baroreceptor 、 Internal medicine 、 Endocrinology 、 Genetic predisposition 、 Salt diet 、 Adrenergic mechanisms 、 Medicine
摘要: The Dahl strain provides a model for examining mechanisms involved in the genetic sensitivity or resistance to salt-induced hypertension. salt-sensitive rats develop hypertension when fed high salt diet; salt-resistant remain normotensive. Based on early experiments, it was thought that epitomized overriding importance of renal and humoral hypertension, but studies past 15 years have demonstrated alterations sympathetic neural also participate critically predisposition rats. This article briefly reviews rats, including evidence role afferent baroreceptor as well central peripheral adrenergic
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