作者: Donald J. Graves , John Lew
DOI:
关键词: Chemistry 、 Biochemistry 、 Proanthocyanidin 、 Tau isoforms 、 Cinnamomum 、 Water soluble
摘要: Compositions comprising proanthocyanidin compositions (e.g. those extracted from cinnamomum species) that are observed to bind tau and inhibit its aggregation as well methods for making using such disclosed. In certain embodiments of the invention, proanthocyanidins can be used a probe identify and/or characterize isoforms in variety contexts. other these designed treat neurological disorders associated with Alzheimer's disease).