Sentinel-Lymphonodektomie beim Vulvakarzinom
作者： P. Hantschmann , H.G. Schnürch , C. Altgassen
DOI: 10.1007/S00761-008-1540-9
关键词: Medicine 、 Primary operation 、 Gynecology
摘要: Die operative Therapie der inguinofemoralen Lymphknoten stellt beim Vulvakarzinom aufgrund wichtigen prognostischen Bedeutung des Nodalstatus und eines therapeutischen Effektes Lymphonodektomie einen obligaten Bestandteil im primaren Behandlungskonzept dar. Andererseits weisen die Patientinnen mit fruhen Vulvakarzinomen meist keine Lymphknotenmetastasen auf, sodass Operation retrospektiv keinen Benefit fur diese erbringt. Dabei ist inguinofemorale einer erheblichen spaten therapiebedingten Morbiditat assoziiert. Sentinel-Lymphonodektomie bietet damit bei ausreichender onkologischer Sicherheit nodalnegative eine Alternative zur Vermeidung Komplikationen, systematischen verbunden sind.
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sci-hub.se 参考文章(21)
David M. Gershenson, Anais Malpica, Mitchell Morris, Merrick I Ross, Thomas W. Burke, Charles F Levenback, Intraoperative lymphatic mapping for vulvar cancer. Obstetrics & Gynecology. ,vol. 84, pp. 163- 167 ,(1994)
H-G. Schnürch, M. Hampl, Diagnostik und Therapie der Lymphknoten bei Tumoren von Vagina und Vulva Onkologe. ,vol. 15, pp. 40- 47 ,(2009) , 10.1007/S00761-008-1539-2
M.H.M. OONK, H. HOLLEMA, J.A. de HULLU, A.G.J. van der ZEE, Prediction of lymph node metastases in vulvar cancer: a review. International Journal of Gynecological Cancer. ,vol. 16, pp. 963- 971 ,(2006) , 10.1111/J.1525-1438.2006.00387.X
Jacobus Van Der Velden, Arnold C. M. Van Lindert, Frits B. Lammes, Fiebo J. W. Ten Kate, Daisy M. D. S. Sie-Go, Hans Oosting, A. Peter M. Heintz, Extracapsular growth of lymph node metastases in squamous cell carcinoma of the vulva. The impact on recurrence and survival Cancer. ,vol. 75, pp. 2885- 2890 ,(1995) , 10.1002/1097-0142(19950615)75:12<2885::AID-CNCR2820751215>3.0.CO;2-3
Pamela J Atherton, Jeff A Sloan, Rising importance of patient-reported outcomes. Lancet Oncology. ,vol. 7, pp. 883- 884 ,(2006) , 10.1016/S1470-2045(06)70914-7
K. N. Gaarenstroom, G. G. Kenter, J. B. Trimbos, I. Agous, F. Amant, A .A. W. Peters, I. Vergote, Postoperative complications after vulvectomy and inguinofemoral lymphadenectomy using separate groin incisions International Journal of Gynecological Cancer. ,vol. 13, pp. 522- 527 ,(2003) , 10.1046/J.1525-1438.2003.13304.X
Frederick B Stehman, Brian N Bundy, Gillian Thomas, Mahesh Varia, Takashi Okagaki, James Roberts, Jeffrey Bell, Paul B Heller, Groin dissection versus groin radiation in carcinoma of the vulva: A gynecologic oncology group study International Journal of Radiation Oncology Biology Physics. ,vol. 24, pp. 389- 396 ,(1992) , 10.1016/0360-3016(92)90699-I
Ramon M. Cabanas, An approach for the treatment of penile carcinoma Cancer. ,vol. 39, pp. 456- 466 ,(1977) , 10.1002/1097-0142(197702)39:2<456::AID-CNCR2820390214>3.0.CO;2-I
Howard D. Homesley, LYMPH NODE FINDINGS AND OUTCOME IN SQUAMOUS CELL CARCINOMA OF THE VULVA Cancer. ,vol. 74, pp. 2399- 2402 ,(1994) , 10.1002/1097-0142(19941101)74:9<2399::AID-CNCR2820740903>3.0.CO;2-V
Tiziano Maggino, Fabio Landoni, Enrico Sartori, Paolo Zola, Angiolo Gadducci, Chiara Alessi, Marika Sold�, Stefania Coscio, Giovanna Spinetti, Andrea Maneo, Annamaria Ferrero, Giuseppe Konishi de Toffoli, Patterns of recurrence in patients with squamous cell carcinoma of the vulva. A multicenter CTF Study. Cancer. ,vol. 89, pp. 116- 122 ,(2000) , 10.1002/1097-0142(20000701)89:1<116::AID-CNCR16>3.0.CO;2-4