Prediction of lymph node metastases in vulvar cancer: a review.

作者: M.H.M. OONK , H. HOLLEMA , J.A. de HULLU , A.G.J. van der ZEE

DOI: 10.1111/J.1525-1438.2006.00387.X

关键词: LymphadenectomySentinel nodeMedicineVulvar CarcinomaPrimary tumorRadiologyVulvar cancerSentinel lymph nodeLymph nodeInternal medicineOncologyInguinofemoral Lymphadenectomy

摘要: The aim of this study was to review the literature on currently available non- and minimally-invasive diagnostic methods analysis primary tumor characteristics for prediction inguinofemoral lymph node metastases in patients with squamous cell carcinoma vulva. We used English language Pubmed reference lists from selected articles. Search terms included vulvar carcinoma, prognosis, metastases, ultrasound, computer tomography, magnetic resonance imaging, positron emission sentinel node. No type restrictions were imposed. Currently no noninvasive imaging techniques exist that are able predict a high enough negative predictive value. A depth invasion ≤1 mm is only histopathologic parameter can exclude complete lymphadenectomy. other clinicopathologic allows exclusion minimally invasive procedure promising technique selecting lymphadenectomy, but its safety has not been proven yet.

参考文章(86)
Alexander Sedlis, Howard Homesley, Brian N. Bundy, Richard Marshall, Edgardo Yordan, Neville Hacker, James H. Lee, Charles Whitney, Positive groin lymph nodes in superficial squamous cell vulvar cancer American Journal of Obstetrics and Gynecology. ,vol. 156, pp. 1159- 1164 ,(1987) , 10.1016/0002-9378(87)90132-3
Barbara L. Andersen, Neville F. Hacker, Psychosexual Adjustment After Vulvar Surgery Obstetrics & Gynecology. ,vol. 62, pp. 457- 462 ,(1983)
M Dias, D Couto, M Gonçalo, C F de Oliveira, E Pinto, Diagnostic value of ultrasound and color Doppler in identifying axillary lymph node metastases in patients with breast cancer. European Journal of Gynaecological Oncology. ,vol. 25, pp. 568- 570 ,(2004)
David M. Gershenson, Anais Malpica, Mitchell Morris, Merrick I Ross, Thomas W. Burke, Charles F Levenback, Intraoperative lymphatic mapping for vulvar cancer. Obstetrics & Gynecology. ,vol. 84, pp. 163- 167 ,(1994)
Joseph Buscema, Jeffrey L. Stern, J.Donald Woodruff, Early invasive carcinoma of the vulva American Journal of Obstetrics and Gynecology. ,vol. 140, pp. 563- 569 ,(1981) , 10.1016/0002-9378(81)90233-7
CHARLES LEVENBACK, THOMAS W. BURKE, MITCHELL MORRIS, ANAIS MALPICA, KRISTIN R. LUCAS, DAVID M. GERSHENSON, Potential Applications of Intraoperative Lymphatic Mapping in Vulvar Cancer Gynecologic Oncology. ,vol. 59, pp. 216- 220 ,(1995) , 10.1006/GYNO.1995.0011
zur Hausen H, Condylomata Acuminata and Human Genital Cancer Cancer Research. ,vol. 36, pp. 794- 794 ,(1976)
C De Cicco, M Sideri, M Bartolomei, C Grana, M Cremonesi, M Fiorenza, A Maggioni, L Bocciolone, C Mangioni, N Colombo, G Paganelli, Sentinel node biopsy in early vulvar cancer British Journal of Cancer. ,vol. 82, pp. 295- 299 ,(2000) , 10.1054/BJOC.1999.0918
J E Gershenwald, M I Colome, J E Lee, P F Mansfield, C Tseng, J J Lee, C M Balch, M I Ross, Patterns of recurrence following a negative sentinel lymph node biopsy in 243 patients with stage I or II melanoma. Journal of Clinical Oncology. ,vol. 16, pp. 2253- 2260 ,(1998) , 10.1200/JCO.1998.16.6.2253