Prospective evaluation of the effect of major depression on working status in a population sample.

摘要: Objective: Numerous surveys have reported associations between major depressive episodes (MDEs) and occupational status, but cross-sectional studies cannot quantify the risks of employment transitions nor clarify their temporal direction. The goal our study was to estimate impact MDE on subsequent status in a longitudinal community cohort. Methods: Data from National Population Health Survey (NPHS) were used. Proportional hazard models logistic regression employed evaluate effect working during 1994 2004 interval among respondents who at job or business baseline. Results: associated with an increased risk movement nonworking status. People aged 26 45 years MDEs more than double this transition (HR = 2.6; 95% CI 1.8 3.6, P Conclusions: is elevated especially people years. Can J Psychiatry. 2009;54(12):841-845. Clinical Implications * Employed depression are twice as likely not be 2 later nondepressed people. Major does affect probability retirement. persists after adjustment for other determinants Limitations NPHS contains little data concerning comorbidity psychiatric disorders. timing relating changes could completely clarified. measure used did contain symptom severity rating. Key Words: episode, disorders, studies, Abbreviations article CIDI-SF Composite International Diagnostic InterviewShort Form episode predictive new unemployment clinical samples.1 European record linkage also documented downward shift toward unemployed patients admitted hospital disorders.2'3 A World Organization Collaborative Study4 case-control study5 provide population-based evidence that increases disablement. strength association using Canadian general population. Methods nationally representative sample assembled by Statistics Canada 1 995. analyses here restricted (n 6570) 65 1994. younger 25 excluded analysis because large proportion (76.8%) they students one interviews. cohort has been interviewed every since and, time analysis, available 10 follow-up, 2004. interview includes CIDI-SF,6 which assesses past-year MDE. items assessing reasons working. Respondents worked (full- part-time) job, either 12 months preceding interview, considered To describe we proportional hazards grouped data. …