作者: David I. Stuart , Claire L. Hill , Timothy F. Booth , B. V. Venkataram Prasad , Jonathan M. Grimes
DOI: 10.1038/9347
关键词: Cypovirus 、 Reoviridae 、 Virus 、 Capsid 、 DsRNA viruses 、 Biology 、 Virology 、 Protein subunit 、 RNA 、 Orthoreovirus
摘要: Cytoplasmic polyhedrosis virus (CPV) is unique among the double-stranded RNA viruses of family Reoviridae in having a single capsid layer. Analysis by cryo-electron microscopy allows comparison shelled CPV and orthoreovirus with high resolution crystal structure inner shell bluetongue (BTV) core. This suggests that novel arrangement identified BTV, 120 protein subunits so-called 'T=2' organization, characteristic us to delineate structural similarities differences between two subgroups — turreted smooth-core viruses. turn coherent picture organization many dsRNA