作者: Harm A.W.M. Tiddens
DOI: 10.1016/J.PRRV.2006.04.002
关键词: Radiology 、 Bronchiectasis 、 Fibrosis 、 Pulmonary function testing 、 Lung 、 Cystic fibrosis 、 Computed tomography 、 Medicine 、 Lung structure 、 High-resolution computed tomography
摘要: Cystic fibrosis (CF) patients demonstrate lung inflammation and infection beginning early in life. Both lead to irreversible structural damage, primarily as bronchiectasis fibrosis. The course of CF varies widely between due genotypic environmental differences. primary aim therapy is prevent or delay damage conserve function. Adequate monitoring disease paramount tailoring treatment a patient's need. Pulmonary function tests (PFTs) are important PFTs, however, only an indirect measure structure insensitive localised damage. By contrast, computed tomography (CT) currently the most sensitive tool monitor structure. As up 50% will have discordant staging when PFTs compared CT findings, both methods needed adequately assess pulmonary condition tailor strategy needs.