作者: Leonie A. Tepper , Pierluigi Ciet , Daan Caudri , Alexandra L. Quittner , Elisabeth M.W.J. Utens
DOI: 10.1002/PPUL.23328
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摘要: Summary Background Computed Tomography (CT) is the gold standard to assess bronchiectasis and trapped air in cystic fibrosis (CF) lung disease, but has disadvantage of radiation exposure. Magnetic Resonance Imaging (MRI) a free alternative. Objective To validate MRI as outcome measure by: correlating scores for with clinical parameters, by comparing those CT scores. Methods In patients CF (aged 5.6–17.4 years), were alternated annually during routine annual check-ups between July 2007 January 2010. Twenty-three children had an performed 1 year prior CT, 34 MRI. Bronchiectasis scored using CF-MRI CF-CT scoring system. correlated parameters: FEV1, Pseudomonas aeruginosa, pulmonary exacerbations patient-reported respiratory symptoms measured on Cystic Fibrosis Questionnaire-Revised (CFQ-R), Spearman's correlation coefficient. compared intra-class coefficients (ICC) Bland–Altman plots. Results Fifty-seven who MRI, CFQ-R study period included. symptoms. only FEV1 aeruginosa. ICCs 0.41 0.35 respectively. tended overestimate CT. Conclusion The associations several important parameters further contributes validation provides different information than CT. Pediatr Pulmonol. © 2015 Wiley Periodicals, Inc.