Validating chest MRI to detect and monitor cystic fibrosis lung disease in a pediatric cohort

作者: Leonie A. Tepper , Pierluigi Ciet , Daan Caudri , Alexandra L. Quittner , Elisabeth M.W.J. Utens

DOI: 10.1002/PPUL.23328

关键词:

摘要: Summary Background Computed Tomography (CT) is the gold standard to assess bronchiectasis and trapped air in cystic fibrosis (CF) lung disease, but has disadvantage of radiation exposure. Magnetic Resonance Imaging (MRI) a free alternative. Objective To validate MRI as outcome measure by: correlating scores for with clinical parameters, by comparing those CT scores. Methods In patients CF (aged 5.6–17.4 years), were alternated annually during routine annual check-ups between July 2007 January 2010. Twenty-three children had an performed 1 year prior CT, 34 MRI. Bronchiectasis scored using CF-MRI CF-CT scoring system. correlated parameters: FEV1, Pseudomonas aeruginosa, pulmonary exacerbations patient-reported respiratory symptoms measured on Cystic Fibrosis Questionnaire-Revised (CFQ-R), Spearman's correlation coefficient. compared intra-class coefficients (ICC) Bland–Altman plots. Results Fifty-seven who MRI, CFQ-R study period included. symptoms. only FEV1 aeruginosa. ICCs 0.41 0.35 respectively. tended overestimate CT. Conclusion The associations several important parameters further contributes validation provides different information than CT. Pediatr Pulmonol. © 2015 Wiley Periodicals, Inc.

参考文章(29)
Martine Loeve, Gabriel P. Krestin, Margaret Rosenfeld, Marleen de Bruijne, Stephen M. Stick, Harm A. Tiddens, Differences in asthma control and management in Europe European Respiratory Journal. ,vol. 42, pp. 212- ,(2013) , 10.1183/09031936.00051512
Colm J. McMahon, Jonathan D. Dodd, Catherine Hill, Neil Woodhouse, Jim M. Wild, Stan Fichele, Charles G. Gallagher, Stephen J. Skehan, Edwin J. R. van Beek, James B. Masterson, Hyperpolarized 3helium magnetic resonance ventilation imaging of the lung in cystic fibrosis: comparison with high resolution CT and spirometry European Radiology. ,vol. 16, pp. 2483- 2490 ,(2006) , 10.1007/S00330-006-0311-5
Harm A.W.M. Tiddens, Chest computed tomography scans should be considered as a routine investigation in cystic fibrosis Paediatric Respiratory Reviews. ,vol. 7, pp. 202- 208 ,(2006) , 10.1016/J.PRRV.2006.04.002
Alan S. Brody, Heidi Sucharew, Jonathan D. Campbell, Steven P. Millard, Paul L. Molina, Jeffrey S. Klein, Joanne Quan, Computed tomography correlates with pulmonary exacerbations in children with cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. ,vol. 172, pp. 1128- 1132 ,(2005) , 10.1164/RCCM.200407-989OC
Wieying Kuo, Pierluigi Ciet, Harm A. W. M. Tiddens, Wei Zhang, R. Paul Guillerman, Marcel van Straten, Monitoring cystic fibrosis lung disease by computed tomography. Radiation risk in perspective. American Journal of Respiratory and Critical Care Medicine. ,vol. 189, pp. 1328- 1336 ,(2014) , 10.1164/RCCM.201311-2099CI
Peter D. Sly, Siobhain Brennan, Catherine Gangell, Nicholas de Klerk, Conor Murray, Lauren Mott, Stephen M. Stick, Philip J. Robinson, Colin F. Robertson, Sarath C. Ranganathan, Lung disease at diagnosis in infants with cystic fibrosis detected by newborn screening. American Journal of Respiratory and Critical Care Medicine. ,vol. 180, pp. 146- 152 ,(2009) , 10.1164/RCCM.200901-0069OC
Sanja Stanojevic, Angie Wade, Janet Stocks, John Hankinson, Allan L. Coates, Huiqi Pan, Mark Rosenthal, Mary Corey, Patrick Lebecque, Tim J. Cole, Reference Ranges for Spirometry Across All Ages: A New Approach American Journal of Respiratory and Critical Care Medicine. ,vol. 177, pp. 253- 260 ,(2008) , 10.1164/RCCM.200708-1248OC
Alan S. Brody, Michael R. Kosorok, Zhanhai Li, Lynn S. Broderick, Jeffrey L. Foster, Anita Laxova, Hari Bandla, Philip M. Farrell, Reproducibility of a scoring system for computed tomography scanning in cystic fibrosis. Journal of Thoracic Imaging. ,vol. 21, pp. 14- 21 ,(2006) , 10.1097/01.RTI.0000203937.82276.CE
Martine Loeve, Maarten H. Lequin, Marleen de Bruijne, Ieneke J. C. Hartmann, Krista Gerbrands, Marcel van Straten, Wim C. J. Hop, Harm A. W. M. Tiddens, Cystic fibrosis: Are volumetric ultra-low-dose expiratory CT scans sufficient for monitoring related lung disease? Radiology. ,vol. 253, pp. 223- 229 ,(2009) , 10.1148/RADIOL.2532090306
Naveen PILLARISETTI, Barry LINNANE, Sarath RANGANATHAN, Early bronchiectasis in cystic fibrosis detected by surveillance CT. Respirology. ,vol. 15, pp. 1009- 1011 ,(2010) , 10.1111/J.1440-1843.2010.01765.X