Conformation of the tridimensional structure of 1,2,3,4,6-pentagalloyl-β-D-glucopyranose (PGG) by (1)H NMR, NOESY and theoretical study and membrane interaction in a simulated phospholipid bilayer: a first insight.
作者： Giangiacomo Beretta , Roberto Artali , Enrico Caneva , Roberto Maffei Facino
DOI: 10.1002/MRC.2718
关键词: Molecular dynamics 、 Bilayer 、 Chemistry 、 Membrane 、 Stereochemistry 、 Lipid bilayer 、 Two-dimensional nuclear magnetic resonance spectroscopy 、 Proton NMR 、 Molecular model 、 Nuclear magnetic resonance spectroscopy
摘要: 1,2,3,4,6-Penta-O-galloyl-β-D-glucopyranose (PGG) is a polyphenolic compound found in substantial amounts number of medicinal herbs. We report (i) its conformational analysis by solution NMR and molecular dynamics calculation (ii) theoretical study interaction with model membrane bilayer. The galloyl groups B E appear to play important roles the phospholipid
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