Système de mutagenèse par transposons et ses méthodes d'utilisation

作者： Aaron M. Geurst , David A. Largaespada , Branden S Moriarity

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摘要: La presente invention concerne des methodes utilisant transposons pour modifier un phenotype d'une cellule in vitro. Une methode peut consister a incuber une comprenant au moins deux et polynucleotide codant transposase l'origine de la transposition l'ADN genomique cellule; observer dans les cellules mutagenisees obtenues. L'invention egalement systeme mutagenese par qui permet d'introduire

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参考文章(22)

David A. Largaespada, Transposon mutagenesis in mice. Methods of Molecular Biology. ,vol. 530, pp. 379- 390 ,(2009) , 10.1007/978-1-59745-471-1_20

A G Uren, J Kool, A Berns, M van Lohuizen, Retroviral insertional mutagenesis: past, present and future Oncogene. ,vol. 24, pp. 7656- 7672 ,(2005) , 10.1038/SJ.ONC.1209043

Vincent W Keng, Kojiro Yae, Tomoko Hayakawa, Sumi Mizuno, Yoshihiro Uno, Kosuke Yusa, Chikara Kokubu, Taroh Kinoshita, Keiko Akagi, Nancy A Jenkins, Neal G Copeland, Kyoji Horie, Junji Takeda, Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system Nature Methods. ,vol. 2, pp. 763- 769 ,(2005) , 10.1038/NMETH795

Kyoung Ah Min, Sang Taek Oh, Kun Ho Yoon, Chong Kook Kim, Suk Kyeong Lee, Prolonged gene expression in primary porcine pancreatic cells using an Epstein-Barr virus-based episomal vector. Biochemical and Biophysical Research Communications. ,vol. 305, pp. 108- 115 ,(2003) , 10.1016/S0006-291X(03)00689-2

R. Rad, L. Rad, W. Wang, J. Cadinanos, G. Vassiliou, S. Rice, L. S. Campos, K. Yusa, R. Banerjee, M. A. Li, J. de la Rosa, A. Strong, D. Lu, P. Ellis, N. Conte, F. T. Yang, P. Liu, A. Bradley, PiggyBac Transposon Mutagenesis: A Tool for Cancer Gene Discovery in Mice Science. ,vol. 330, pp. 1104- 1107 ,(2010) , 10.1126/SCIENCE.1193004

Adam J. Dupuy, Keiko Akagi, David A. Largaespada, Neal G. Copeland, Nancy A. Jenkins, Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system Nature. ,vol. 436, pp. 221- 226 ,(2005) , 10.1038/NATURE03691

M. O. Bradley, A. R. Kraynak, R. D. Storer, J. B. Gibbs, Experimental metastasis in nude mice of NIH 3T3 cells containing various ras genes. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 83, pp. 5277- 5281 ,(1986) , 10.1073/PNAS.83.14.5277

M Conese, C Auriche, F Ascenzioni, Gene therapy progress and prospects: episomally maintained self-replicating systems. Gene Therapy. ,vol. 11, pp. 1735- 1741 ,(2004) , 10.1038/SJ.GT.3302362

T. K. Starr, P. M. Scott, B. M. Marsh, L. Zhao, B. L. N. Than, M. G. O'Sullivan, A. L. Sarver, A. J. Dupuy, D. A. Largaespada, R. T. Cormier, A Sleeping Beauty transposon-mediated screen identifies murine susceptibility genes for adenomatous polyposis coli (Apc)-dependent intestinal tumorigenesis Proceedings of the National Academy of Sciences of the United States of America. ,vol. 108, pp. 5765- 5770 ,(2011) , 10.1073/PNAS.1018012108

10.

Caiping Ren, Ming Zhao, Xuyu Yang, Dongsheng Li, Xingjun Jiang, Lei Wang, Wenjiao Shan, Hong Yang, Liang Zhou, Wen Zhou, Hongbo Zhang, None, Establishment and applications of epstein-barr virus-based episomal vectors in human embryonic stem cells. Stem Cells. ,vol. 24, pp. 1338- 1347 ,(2006) , 10.1634/STEMCELLS.2005-0338

Système de mutagenèse par transposons et ses méthodes d'utilisation

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Système de mutagenèse par transposons et ses méthodes d'utilisation

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