Health history after intrahepatic cholestasis of pregnancy

作者: KAISA TURUNEN , ANNI MÖLSÄ , KRISTIINA HELANDER , MARKKU SUMANEN , KARI J. MATTILA

DOI: 10.1111/J.1600-0412.2012.01403.X

关键词: PediatricsPopulationHepatobiliary diseaseCohort studyCholestasis of pregnancyQuestionnaireHepatobiliary DisorderMedical diagnosisMedicineBreast cancerGynecology

摘要: Objective. To establish whether intrahepatic cholestasis of pregnancy (ICP) is associated with other diseases during a woman's lifetime. Design. Prospective controlled cohort study. Setting. University Hospital in Finland. Population. A total 575 women ICP and 1374 control women, all having delivered 1969–1988. Questionnaires were sent to 544 patients 1235 women. Responses received from 1178 (66.4%). Methods. Questionnaire survey autumn 2010. Main outcome measures. Perceived health, symptoms complaints, diagnosed by doctor use medicines. Results. No statistically significant differences detected perceived health. Differences recent complaints small. Diagnoses made showed higher frequencies the group than for hepatobiliary diseases, breast cancer hypothyreosis. Diagnosed hypertension high cholesterol requiring medication as well cardiac arrhythmia less frequent group. Women this used antacid medicines more often Conclusions. There few between except frequency later disease, history should be screened hypothyreosis readily those without. The warrants further research.

参考文章(26)
Sue Wilson, James V. Parle, Lesley M. Roberts, Andrea K. Roalfe, F. D. Richard Hobbs, Penny Clark, Michael C. Sheppard, Michael D. Gammage, Helen M. Pattison, Jayne A. Franklyn, , Prevalence of subclinical thyroid dysfunction and its relation to socioeconomic deprivation in the elderly: a community-based cross-sectional survey. The Journal of Clinical Endocrinology and Metabolism. ,vol. 91, pp. 4809- 4816 ,(2006) , 10.1210/JC.2006-1557
Frank Lammert, Hanns-Ulrich Marschall, Anna Glantz, Siegfried Matern, Intrahepatic cholestasis of pregnancy: molecular pathogenesis, diagnosis and management Journal of Hepatology. ,vol. 33, pp. 1012- 1021 ,(2000) , 10.1016/S0168-8278(00)80139-7
Anne Ropponen, Reijo Sund, Seija Riikonen, Olavi Ylikorkala, Kristiina Aittomäki, Intrahepatic cholestasis of pregnancy as an indicator of liver and biliary diseases: a population-based study. Hepatology. ,vol. 43, pp. 723- 728 ,(2006) , 10.1002/HEP.21111
Anna Glantz, Hanns-Ulrich Marschall, Lars-�ke Mattsson, Intrahepatic cholestasis of pregnancy: Relationships between bile acid levels and fetal complication rates. Hepatology. ,vol. 40, pp. 467- 474 ,(2004) , 10.1002/HEP.20336
Johanna Laukkarinen, Gediminas Kiudelis, Marko Lempinen, Sari Räty, Hanna Pelli, Juhani Sand, Esko Kemppainen, Caj Haglund, Isto Nordback, Increased Prevalence of Subclinical Hypothyroidism in Common Bile Duct Stone Patients The Journal of Clinical Endocrinology and Metabolism. ,vol. 92, pp. 4260- 4264 ,(2007) , 10.1210/JC.2007-1316
Kaisa Turunen, Markku Sumanen, Riitta-Liisa Haukilahti, Pertti Kirkinen, Kari Mattila, Good pregnancy outcome despite intrahepatic cholestasis Scandinavian Journal of Primary Health Care. ,vol. 28, pp. 102- 107 ,(2010) , 10.3109/02813431003784001
Bertel Berg, Göran Helm, Lennart Petersohn, Nils Tryding, Cholestasis of Pregnancy: Clinical and Laboratory Studies Acta Obstetricia et Gynecologica Scandinavica. ,vol. 65, pp. 107- 113 ,(1986) , 10.3109/00016348609158363
Alfredo M Germain, Jorge A Carvajal, Juan Carlos Glasinovic, Kato C Sumie, Catherine Williamson, Intrahepatic cholestasis of pregnancy: an intriguing pregnancy-specific disorder Journal of the Society for Gynecologic Investigation. ,vol. 9, pp. 10- 14 ,(2002) , 10.1016/S1071-5576(01)00144-7
Timo Laatikainen, Annika Tulenheimo, Maternal serum bile acid levels and fetal distress in cholestasis of pregnancy International Journal of Gynecology & Obstetrics. ,vol. 22, pp. 91- 94 ,(1984) , 10.1016/0020-7292(84)90019-5