Hippocampal and neocortical interactions during context discrimination: electrophysiological evidence from the rat.

摘要: There is substantial evidence that hippocampus plays an important role in the processing of contextual information. Its specific role, however, remains unclear. One possibility single hippocampal neurons represent context information so local circuits can construct representations current context, and expected based on past experience. Population codes derived from input by multiple may then engage match-mismatch algorithms compare to determine extent which has changed. The results such comparisons be used discriminate contexts. When changes are detected, efferent messages passed connected neocortical areas informed "decisions" regarding future behavioral cognitive strategies made. Here, a brief review describes primary consequence discrimination meaningful Then, functional significance likely receive output described terms their contribution control ongoing strategy, especially during active navigation. It clear this systems view studies spatial navigation continue provide researchers with excellent model hippocampal-neocortical interactions learning.