作者: Helen Wood , Andrew Dickman , Angela Star , Jason W Boland
DOI: 10.7861/CLINMEDICINE.18-1-17
关键词: Duloxetine 、 Cancer pain 、 Pain assessment 、 Opioid 、 Intensive care medicine 、 Pregabalin 、 Medicine 、 Gabapentin 、 Tapentadol 、 Palliative care
摘要: Pain is a common symptom in many types of cancer. Interdisciplinary team management, including pain assessment, explanation to the patient/family, treating reversible, non-pharmacological treatments and reassessment are essential. This article focuses on pharmacological management cancer pain, overviews updates recent advances this field. Both non-opioid opioid analgesia as well coanalgesics (adjuvants) reviewed. Within risks non-steroidal anti-inflammatory drugs (NSAIDs) considered recommendations for NSAIDs patients at risk gastrointestinal cardiovascular toxicity made. For analgesics, side effects opioids discussed alongside practical guidance prescribing converting between opioids. Newer such tapentadol update. Amitriptyline, duloxetine, gabapentin pregabalin, their use reviewed section.