Diffusion-weighted imaging volume as the best predictor of the diffusion-perfusion mismatch in acute stroke patients within 8 hours of onset.
作者： Junya Aoki , Yohei Tateishi , Christopher L. Cummings , Esteban Cheng-Ching , Paul Ruggieri
DOI: 10.1111/JON.12107
关键词: Fluid-attenuated inversion recovery 、 Stroke patient 、 Diffusion MRI 、 Volume (compression) 、 Nuclear medicine 、 Acute stroke 、 Odds ratio 、 Medicine 、 Perfusion 、 Endovascular therapy
摘要: BACKGROUND Diagnostic accuracies of standard NCCT, CTA, CTA-SI, FLAIR, and DWI to detect the diffusion‐perfusion mismatch (DPM) were compared. METHODS Stroke patients considered for endovascular therapy within 8 hours onset enrolled. DPM was defined as at least 160% between PWI volume. RESULTS seen in 35 (71%) 49 patients. ASPECTS on 9 (8-9), (6-9), 7 (5-9) group, 6 (4-9), (2-7), 5 (2-6) nonmismatch respectively (P = .027, .006, .001). Ischemic volume CTA-SI 4.6 (.2-13.0) cm 3 21.5 (9.7-44.0) 61.5 (6.6-101.1) 94.9 (45.7-139.8) group .003 <.001). Significant collateralization FLAIR 80% 88% 42% 58% .026 .039). Odds ratios (95% CI) 70 predict 30.17 (2.06-442.41) after adjusting ASPECTSs DWI, 44.90 (2.75-732.73) ischemic 42.80 (3.05-601.41) significant .013, .008, .005). CONCLUSIONS best predictor DPM.
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