Are protein domains modules of lateral genetic transfer

摘要: Background: In prokaryotes and some eukaryotes, genetic material can be transferred laterally among unrelated lineages recombined into new host genomes, providing metabolic physiological novelty. Although the process is usually framed in terms of gene sharing (e. g. lateral transfer, LGT), there little reason to imagine that units transfer recombination correspond entire, intact genes. Proteins often consist one or more spatially compact structural regions (domains) which may fold autonomously which, singly combination, confer protein's specific functions. As LGT frequent strongly selective environments natural selection based on function, we hypothesized domains might also serve as modules i.e. DNA are between encode proteins.