Incorporating Demand and Supply Constraints into Economic Evaluations in Low-Income and Middle-Income Countries.

摘要: Global guidelines for new technologies are based on cost and efficacy data from a limited number of trial locations. Country-level decision makers need to consider whether cost-effectiveness analysis used inform global sufficient their situation or use models that adjust results taking into account setting-specific epidemiological heterogeneity. However, demand supply constraints will also impact by influencing the standard care implementation any technology. These may vary substantially setting. We present two case studies economic evaluations introduction diagnostics malaria tuberculosis control. analyse how scope each technology expanded then address over time. these conceptual framework can be explore characteristics intervention complexity influence constraints. Finally, we describe feasible steps researchers who wish apply our in analyses.