A hierarchy of timescales in protein dynamics is linked to enzyme catalysis
作者： Katherine A. Henzler-Wildman , Ming Lei , Vu Thai , S. Jordan Kerns , Martin Karplus
DOI: 10.1038/NATURE06407
关键词: Folding (chemistry) 、 Enzyme catalysis 、 Biochemistry 、 Dynamics (mechanics) 、 Macromolecule 、 Chemistry 、 Chemical physics 、 Molecular dynamics 、 Function (biology) 、 Protein dynamics 、 Adenylate kinase
摘要: … where local backbone conformation must change for lid motion to … , backbone and side chain, participate collectively; here we have only measured atomic dynamics for the backbone …
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