Controlled release combination of carbidopa/levodopa

作者: Scott A. Reines , Donald W. Nibbelink , Edward C. Scholtz , Robert E. Dempski

DOI:

关键词: Over treatmentCarbidopa/levodopaControlled releasePharmacologyLevodopaCarbidopaDrugChemistryDrug delivery

摘要: A matrix or monolithic drug delivery system for the controlled release of carbidopa and levodopa consists two drugs uniformly dispersed in a polymer vehicle at concentration that is greater than solubility either polymer. Treatment parkinsonism with formulation provides several advantages over treatment standard carbidopa/levodopa combinations presently employed.

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