作者: Scott A. Reines , Donald W. Nibbelink , Edward C. Scholtz , Robert E. Dempski
DOI:
关键词: Over treatment 、 Carbidopa/levodopa 、 Controlled release 、 Pharmacology 、 Levodopa 、 Carbidopa 、 Drug 、 Chemistry 、 Drug delivery
摘要: A matrix or monolithic drug delivery system for the controlled release of carbidopa and levodopa consists two drugs uniformly dispersed in a polymer vehicle at concentration that is greater than solubility either polymer. Treatment parkinsonism with formulation provides several advantages over treatment standard carbidopa/levodopa combinations presently employed.