Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection
作者： Christopher B Ford , Philana Ling Lin , Michael R Chase , Rupal R Shah , Oleg Iartchouk
DOI: 10.1038/NG.811
关键词: Biology 、 Single-nucleotide polymorphism 、 Whole genome sequencing 、 Mutation 、 Mycobacterium tuberculosis 、 Virology 、 Genetics 、 Mutation rate 、 Isoniazid 、 Tuberculosis 、 Latent tuberculosis
摘要: Tuberculosis poses a global health emergency, which has been compounded by the emergence of drug-resistant Mycobacterium tuberculosis (Mtb) strains. We used whole-genome …
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