作者: Zhou Junmei , Li Lingling , Li Qian
DOI:
关键词: Thermal Hyperalgesia 、 Drug 、 Pharmacology 、 Intrathecal 、 Neuralgia 、 Medicine 、 Inflammatory pain 、 Antagonist 、 Mechanical Allodynia
摘要: The invention relates to an application of IL-36R antagonist in preparing a pain-relieving drug. finds that intrathecally taken is capable relieving the painful behavior responses, including mechanical allodynia and thermal hyperalgesia, rat inflammatory pain neuralgia, quickly becoming effective greatly long lasting time, so can be used as composition drug, further prepared into drug for clinically treating pain, especially neuralgia.